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Pharmaceutical Grade PVP

Product Name:Polyvinylpyrrolidone

 
Chemical Description:Homopolymer of 1-Vinly-2-Pyrrolidone,Polyvinylpyrrolidone,PVP
 
INCI/CTFA:PVP
 
Pharmacopeia Name:Povidone(Povidonum)
 
CAS NO.:9003-39-8
 
Formula structure:
 
       
Product Properties: Povidone is a hygroscopic polymer ,supplied in white to creamy white powder or flakes,ranging from low to high viscosity & low to high molecular weight,which characterized by K Value.It’s easily soluble in water and many other organic solvents,with excellent hygroscopisty,film-forming,adhesive,chemical stability and toxicological safeness characters.
 
Applications:Povidone is one of the most important excipients in the worldwide for pharmaceutical industry,whatever for human health care products and animal health care products.Which used as:1)Binder for tables,capsule,2)Sugar coatings and films,3)Thickening agent,4)Solubility Improver for poorly soluble drugs,5)Bioavailability Enhancer for drug’s active ingredients,6)Pore-forming for membrane products.
 
Specifications:
Product
Povidone K15
Povidone K17
Povidone K25
Povidone K30
Povidone K60
Povidone K90
Appearance
White or yellowish-white,hygroscopic powder or flakes
Solubility
Freely soluble in water,in ethano(96%) and in methanol,very slightly soluble in acetone.
Appearance of Solution
Clearly and not moren intensely coloured than reference solution B6,BY6 or R6
Identifications
Meet ID Tests
pH Value(5% in aqueous solution)
3.0-5.0
3.0-5.0
3.0-5.0
3.0-5.0
4.0-7.0
4.0-7.0
Viscosity(Expressed as K Value)
12.75-17.25
15.3-18.36
22.5-27.0
27.0-32.4
54.0-64.8
81.0-97.2
Adehydes(Expressed as Acetaldehyde)
500 ppm max.
500 ppm max.
500 ppm max.
500 ppm max.
500 ppm max.
500 ppm max.
Peroxides(Expressed as H2O2)
400ppm max.
400 ppm max
400 ppm max
400 ppm max
400 ppm max
400 ppm max
Formic Acid
0.5% max.
0.5% max.
0.5% max.
0.5% max.
0.5% max.
0.5% max.
Hydrazine
1ppm max.
1ppm max.
1ppm max.
1ppm max.
1ppm max.
1ppm max.
 
N-Vinylpyrrolidone(Impurity A)
USP26
1000 ppm max.
1000 ppm max.
1000 ppm max.
1000 ppm max.
1000 ppm max.
1000 ppm max.
Current USP/EP/BP
10 ppm max.
10 ppm max.
10 ppm max.
10 ppm max.
10 ppm max.
10 ppm max.
2-Pyrrolidone(Impurity B)
3.0% max.
3.0% max.
3.0% max.
3.0% max.
3.0% max.
3.0% max.
Heavy Metals(as Pb)
10 ppm max.
10 ppm max.
10 ppm max.
10 ppm max.
10 ppm max.
10 ppm max.
Water
5.0% max.
5.0% max.
5.0% max.
5.0% max.
5.0% max.
5.0% max.
Sulphated Ash
0.1% max.
0.1% max.
0.1% max.
0.1% max.
0.1% max.
0.1% max.
Nitrogen Content
11.5-12.8%
11.5-12.8%
11.5-12.8%
11.5-12.8%
11.5-12.8%
11.5-12.8%



Contact Us

Jiaozuo Zhongwei Special Products Pharmaceutical Co.,Ltd.
Add:No.115,Xinyuan-Dong Road,Wen Town,Jiaozuo,Henan,454800,China
Tel:+86-13127530809
Fax:86-391-6109918
E-mail: sales@zw-pvp.com
International Business:
E-mail: sales@zw-pvp.com

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